Origins and Purpose
Ome Central is developed and co-led by physician researchers at Ann & Robert H. Lurie Children’s Hospital of Chicago who are faculty at the Northwestern University Feinberg School of Medicine. Their careers in medical and public health investigation span the spectrum of clinical and translational research – from basic science, to clinical science, to health systems and policy applications.
The overarching purpose of Ome Central is to foster dialogue and promote broad use of -ome-based names for biological, environmental, and social domains that affect human health in the evolving era of precision medicine. By serving as a dynamic source of information about -omes and the -omics through which they are measured, Ome Central is designed to serve as reference for scientists, clinicians, and the public.
Ome Central is a not-for-profit initiative funded by its founders, operated solely for the purposes stated above.
Matthew M. Davis, MD, MAPP, is the A Todd Davis Professor and Division Head of Academic General Pediatrics and Primary Care, Director of the Mary Ann & J. Milburn Smith Child Health Research Program, and Associate Chief Research Officer for Health Services and Policy Research at the Stanley Manne Children’s Research Institute of the Ann & Robert H. Lurie Children’s Hospital of Chicago. He serves as Professor of Pediatrics and Medical Social Sciences at the Northwestern University Feinberg School of Medicine. During his career, Dr. Davis has received extramural funding for his research from the National Institutes of Health, National Science Foundation, Centers for Disease Control and Prevention, Agency for Healthcare Research and Quality, Bill & Melinda Gates Foundation, Robert Wood Johnson Foundation, and WK Kellogg Foundation, and has published over 200 peer-reviewed articles and over 100 issue briefs. He has been honored with the 2006 national Nemours Award for Child Health Services Research and the 2015 Distinguished Service Award from the Regents of the University of Michigan. He is a graduate of Harvard Medical School, completed his residency training in pediatrics at Boston Children’s Hospital and in internal medicine at Brigham and Women’s Hospital, and then completed a master of arts degree in public policy at the Harris School of the University of Chicago, where he also trained as a Robert Wood Johnson Clinical Scholar.
Thomas P. Shanley, MD, FCCM, is the Founders’ Board Centennial Professor and Chairman of the Department of Pediatrics at the Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine, where he also serves as Chief Research Officer of the Stanley Manne Children’s Research Institute. Dr. Shanley received his medical degree from the Pritzker School of Medicine at the University of Chicago and served as a resident and chief resident in Pediatrics at the Children’s Hospital of Philadelphia. He was an NIH Research Fellow under the auspices of the Pediatric Scientist Development Program at the University of Michigan in the laboratory of Dr. Peter Ward studying the regulation of inflammation in acute lung injury. Dr. Shanley moved to Cincinnati Children’s Hospital Medical Center were he established a research program focused on signal transduction in critical illness and critical pathways affected by host-pathogen interactions. He returned to the University of Michigan as Director of Pediatric Critical Care Medicine in August 2004 and also served as the Director of Clinical and Translational Research for the Department. He was named Associate Dean for Clinical and Translational Research and Director of the Michigan Institute for Clinical and Health Research which housed the University’s Clinical Translational Science Award from the National Center for Advancing Translational Sciences, a position he held from 2011 to his move to Lurie Children’s Hospital. Dr. Shanley’s research is directed towards improving our understanding of the molecular basis of pediatric sepsis by taking a comprehensive approach spanning the translational spectrum. His translational research is directed at determining the role of post-translational histone modifications in altering gene expression after sepsis. Nationally, he served as Secretary-Treasurer for the Society for Pediatric Research and the Federation of Pediatric Organizations and currently he serves as an SPR Trustee to the International Pediatric Research Foundation. He also served as a member of the innaugural Steering Committee for NCATS from 2013-2015 during which he co-led the Enhancing Clinical Research Professionals’ Training and Qualification project.
Ome Central is grateful for the technical support of webmaster Krishna Davis.